| OSN 2022 | SMA | Informatika | | Devanrio Geofendra | SMA IGNATIUS GLOBAL SCHOOL | | |
| Muhammad Ilham Syafik | MAN INSAN CENDEKIA | | |
| Matematika | 30 | Nicholas Eric Syuhendra | SMA IGNATIUS GLOBAL SCHOOL | | Perunggu |
| Yuan Komah | SMA IGNATIUS GLOBAL SCHOOL | | |
| Demetrio Franklyn Edryan | SMA KUSUMA BANGSA PALEMBANG | | |
| Fisika | | Zaki Fathi Fahrizal | SMA IGNATIUS GLOBAL SCHOOL | | |
| Felix Salim | SMA IGNATIUS GLOBAL SCHOOL | | |
| Nessa Amaris Susanto | SMA XAVERIUS 1 PALEMBANG | | |
| Kimia | | Anjani Faluvy | SMA NEGERI 15 OKU | | |
| Biologi | | Fazli Mawla Pradi | MAN INSAN CENDEKIA | | |
| Olivia Meifelia | SMA IGNATIUS GLOBAL SCHOOL | | |
| Astronomi | | Sayyid Daffa ' Al Mubarok | MAN 3 PALEMBANG | | |
| Muhammad Dzaki Rozani | MAN INSAN CENDEKIA | | |
| Ekonomi | 26 | Chrisella | SMA IGNATIUS GLOBAL SCHOOL | | Perunggu |
| Joviera Invi Gozali | SMA KUSUMA BANGSA PALEMBANG | | |
| Nabilah Basyasyah | SMAN 1 PALEMBANG | | |
| Geografi | | Naila Indana Lazulfa | SMA KUSUMA BANGSA PALEMBANG | | |
| Kebumian | | Annisa Retno Kurniasari | MAN INSAN CENDEKIA | | |
| SMP | Matematika | 17 | Muhammad Atala Assyikur | SMP IT HARAPAN MULIA PALEMBANG | | Perak |
| Alisyah Nicky Aflah | SMP NEGERI 2 TEBING TINGGI | | |
| Angel Susanto | SMP XAVERIUS 01 PALEMBANG | | |
| IPA | | Naisyah Putu Luthfiya | SMP ISLAM AL - FAHD | | |
| Mutiara Nauli | SMP NEGERI 2 OGAN KOMERING ULU | | |
| Haqqiliyuzh Yaubi | SMP NEGERI 1 BABAT TOMAN | | |
| Shere Ignasio Siahaan | SMP XAVERIUS 01 PALEMBANG | | |
| Cahaya Intan Purwari | SMPN 5 LUBAI ULU | | |
| IPS | 16 | Rheisya Andreanisa | SMPN 1 TALANG UBI | | Perak |
| 35 | Jiyhan Kayfa Zahrah | SMP SINGAPORE INDONESIAN SCHOOL | | Perunggu |
| M. Alvin Al Farizi | SMPN 1 SUNGAI LILIN | | |
| Anjelie | SMPN 1 SEKAYU | | |
| Zulfa Khairunnisa | SMPN 1 BABAT SUPAT | | |
| Dewanti Aqila Hafiza | SMP EMIRATES ISLAMIC SCHOOL | | |
| Janice Richelle Han | SMP XAVERIUS BATURAJA | | |
| Valezka Isabel Paulina | SMP KRISTEN IPEKA PALEMBANG | | |
| SD | Matematika | 24 | Syakira Nailah Ramadhani | SD IT HARAPAN MULIA PALEMBANG | | Perunggu |
| 37 | Oziel Halim Mushlih Pratama | SD MUHAMMADIYAH 1 PAGAR ALAM | | Hon. Mention |
| IPA | | Marsha Dzakirah Edie | SD IT HARAPAN MULIA PALEMBANG | | |