| OSN 2022 | SMA | Informatika | | Benedict Dustin Tanex | SMA KRISTEN EBEN HAEZAR MANADO | | |
| Matematika | | Harvest Ecclesiano Christ Walukow | SMA LOKON ST. NICOLAUS TOMOHON | | |
| Fisika | | Miracle Pascal Gunarsih | SMA MIS KOLONGAN | | |
| Kimia | 36 | Benedict Aurelius Tjia | SMA MIS KOLONGAN | | Hon. Mention |
| Biologi | | Lingkan Elaia Sangiangkila Turangan | SMA LENTERA HARAPAN TOMOHON | | |
| Astronomi | | Celfin Antonius Villareal Sompotan | SMA LOKON ST. NICOLAUS TOMOHON | | |
| Ekonomi | 20 | Rafa Zulhaq Rizaldi | SMA NEGERI 1 MANADO | | Perunggu |
| Geografi | | David Samuel Joy Wangkai | SMA NEGERI 9 MANADO | | |
| Kebumian | | Jesslyn Viola Widjanarko | SMA MIS KOLONGAN | | |
| SMP | Matematika | | Reivaldy Sephio Rafael Paundanan | SMP KRISTEN TABITA | | |
| Daniel Glorio Alessandro Maralending | SMP NEGERI 1 TAHUNA | | |
| Amanah Pangurisang | SMP NEGERI 3 SATAP KENDAHE | | |
| Nata Nugraha | SMP NEGERI 13 MANADO | | |
| Axelleon Reinhart Tandani | SMP KRISTEN EBEN HAEZAR 1 | | |
| IPA | | Aurelle Kathleen Limmunandar | SMP MANADO INDEPENDENT SCHOOL | | |
| Renata Rebeca Miracle Sipayung | SMP NEGERI 2 BITUNG | | |
| IPS | 32 | Kayla Kasiman | SMP KRISTEN EBEN HAEZAR 1 | | Perunggu |
| Atifah Abdun | SMP NEGERI 2 BELANG | | |
| Ridho Abdillah Bawono | SMP NEGERI 10 MANADO | | |
| Gisela Maria Rahman | SMP KATOLIK STELLA MARIS TOMOHON | | |
| SD | Matematika | | Melisa Ivanna Pinontoan | SD NEGERI 1 AIRMADIDI | | |
| IPA | | Mathew Davino Sualang | SD INPRES WONGKAI | | |